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제43회 정기학술대회에 많은 관심과 참여를 부탁드립니다.


Writer 한국발생생물학회 Date 2020-12-31 09:10:02 Hits 698


The Fleischer Institute for Diabetes and Metabolism

Division of Endocrinology, Department of Medicine

Department of Molecular Pharmacology,

Albert Einstein College of Medicine, NY, USA


The brain regulates food intake via a complex interplay of circuit mechanisms. Dysfunction in these mechanisms can lead to overconsumption and obesity. Because obesity and its associated health problems are reaching epidemic proportions, elucidation of the neural mechanisms regulating caloric intake is of paramount importance.

The hypothalamus is a key element of the neural circuits that regulate food intake. Specific neuronal populations within the hypothalamus are sensitive to a variety of homeostatic indicators, such as circulating nutrient levels, as well as hormones (e.g., insulin, ghrelin, leptin) that signal circulating glucose, gut nutrient, and body fat content. Because understanding caloric intake regulation is of critical importance for the development of physiological interventions that treat and prevent obesity, neuroscientists have recently focused a great deal of attention towards elucidating the functional role of defined hypothalamic neuronal populations in the regulation of food consumption. A major component of this undertaking is to identify all of the relevant neuronal populations and determine how they are interconnected.

My research program focuses on studying the neurobiology of energy metabolism in general and hypothalamic neural mechanisms associated with metabolic dysregulation and obesity in particular. I’m currently mapping the melanocortinergic neural circuits that control overall energy metabolism and the autonomic sensory and motor nervous systems that regulate liver function. Interested candidates should be passionate about research, have the desire to establish her/himself as an independent investigator, and be willing to go above and beyond to accomplish a research goal. My recent publications are the following:

  1. Kwon, E., Joung H.-Y., Liu, S. M., Chua, S. C., Jr., Schwartz, G. J., and Jo, Y. H. Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production. Nature Commun (Dec. 2020); 11(1):6295. doi: 10.1038/s41467-020-20160-w
  2. Jeong, J. H., Chang, J. S., and Jo, Y. H. Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice. Sci Rep 8, no. 1 (Apr. 27 2018): 6672.
  3. Jeong, J. H., Lee, D. K., Liu, S. M., Chua, S. C. Jr., Schwartz, G. J., and Jo, Y. H. Activation of temperature-sensitive Trpv1-like receptors in arc POMC Neurons reduces food intake. PLoS Biol 16, no. 4 (Apr. 2018): e2004399 (selected as a Research highlight in Nature, Top 10% cited article in PLOS biology in 2018-2019, Featured article in PLOS Biology)
  4. Lee, D. K., Jeong, J. H., Chun, S. K., Chua, S.C.Jr., and Jo, Y. H. Interplay between glucose and leptin signaling determines the strength of GABAergic synapses at POMC neurons. Nat Commun 6 (Mar. 2015): 6618.

Contact information:

Young-Hwan JO, PhD

Associate Professor of Medicine and Molecular Pharmacology

Email: young-hwan.jo@einsteinmed.org


한국발생생물학회 홈페이지 회원가입 안내


홈페이지 회원가입 관련하여 안내드립니다.

홈페이지 가입은 정식회원이 되기 전의 절차로, '연회비'를 납부하셔야 정식회원으로 인정받으실 수 있습니다.

정회원/학생회원이 되기 위해서는 '학술행사'→'등록 및 결제시스템'에서 연회비를 결제해주시기를 부탁드립니다.

한국발생생물학회에 많은 관심과 지원을 부탁드립니다.


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제43회 한국발생생물학회 정기학술대회 안내

2024년도 제43회 한국발생생물학회 정기학술대회를 아래와 같이 개최합니다.

정기학술대회 관련 정보를 안내드리오니 적극적인 관심과 많은 참여를 부탁드립니다.

학술대회 안내

1. 주제 : Cellular Dynamics and Evolutionary Aspects in Developmental Biology
2. 일자 : 2024년 8월 22일(목) – 24일(토)
3. 장소 : 경북대학교 글로벌플라자 1층 경하홀
4. 주최 : (사)한국발생생물학회
5. 초록 접수 기간 : 2024년 6월 24일~7월 27일
6. 사전 등록 기간 : 2024년 6월 24일~7월 27일
※세부 일정 및 등록 기간은 해당 공지사항을 통하여 지속적으로 업데이트해 드리겠습니다.

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